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STEMCELL_6A

Does Magnesium Lead to Better Outcomes in Stroke?

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ALCO EMS

Alameda County EMS is a high performance EMS system located in the Bay Area of Northern California.There are over 140,000 9-1-1 call each year in the system.
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Previous studies have shown that magnesium sulfate can act as a possible neuroprotective agent in stroke [1]. Magnesium seemed to be potentially beneficial if given in the first 3 hours, but lacked benefit when given after 7 hours [1]. “Prehospital Use of Magnesium Sulfate as Neuroprotection in Acute Stroke” is a study released in the New England Journal of Medicine this year that attempted to look at both the efficacy of magnesium sulfate as a neuroprotective agent as well as the feasibility of early administration of potential neuroprotective agents in the prehospital setting. The study found no difference in neurologic outcomes or mortality in stroke patients who received magnesium vs. those who received placebo. The study did demonstrate that it was possible to deliver magnesium within 2 hours of symptom onset in the prehospital setting [2]. Continue Reading…